OpenOnco

Openonco Compare Ecd

Compare multiple ECD (Early Cancer Detection) tests side-by-side. Returns key metrics for multiple tests in a tabular comparison format. Use this when users want to compare screening tests or evaluate MCED options (e.g., "Compare Galleri vs Shield vs CancerSEEK"). Tip: Use openonco_search_ecd first to find test IDs, then compare. Include 'listPrice' in metrics for cost comparison. Default metrics: name, vendor, testScope, sensitivity, specificity, stageISensitivity, ppv, npv, listPrice, fdaSt

Openonco Compare Hct

Compare multiple HCT (Hereditary Cancer Testing) tests side-by-side. Returns key metrics for multiple tests in a tabular comparison format. Use this when users want to compare hereditary cancer panels or evaluate gene coverage across different vendors. Tip: Use openonco_search_hct first to find test IDs, then compare. Include 'genesAnalyzed' in metrics to compare panel sizes. Default metrics: name, vendor, genesAnalyzed, cancerTypes, sampleType, tat, listPrice, fdaStatus. Returns JSON array o

Openonco Compare Mrd

Compare multiple MRD (Molecular Residual Disease) tests side-by-side. Returns key metrics for multiple tests in a tabular comparison format. Use this when users want to compare specific MRD tests or need help choosing between options (e.g., "Compare Signatera vs Guardant Reveal"). Tip: Use openonco_search_mrd first to find test IDs, then compare. Specify custom 'metrics' to focus on specific attributes. Default metrics: name, vendor, sensitivity, specificity, lod, initialTat, followUpTat, fda

Openonco Compare Tds

Compare multiple TDS (Treatment Decision Support) tests side-by-side. Returns key metrics for multiple tests in a tabular comparison format. Use this when users want to compare CGP panels or evaluate gene coverage and FDA companion diagnostic approvals across options. Tip: Use openonco_search_tds first to find test IDs, then compare. Include 'fdaCompanionDxCount' to see regulatory approval breadth. Default metrics: name, vendor, productType, genesAnalyzed, fdaCompanionDxCount, tat, listPrice,

Openonco Count Ecd

Count ECD (Early Cancer Detection) tests with optional grouping. Get aggregate statistics about ECD tests. Use this to answer questions like "How many MCED tests exist?" or "How many tests per vendor?" Without group_by: returns {"total": N} With group_by: returns {"total": N, "by_{field}": {"value1": count, ...}} Tip: group_by='testScope' shows Single-cancer vs Multi-cancer breakdown.

Openonco Count Hct

Count HCT (Hereditary Cancer Testing) tests with optional grouping. Get aggregate statistics about HCT tests. Use this to answer questions like "How many hereditary cancer tests are available?" or "How many tests per vendor?" Without group_by: returns {"total": N} With group_by: returns {"total": N, "by_{field}": {"value1": count, ...}} Tip: group_by='vendor' shows distribution across testing companies.

Openonco Count Mrd

Count MRD (Molecular Residual Disease) tests with optional grouping. Get aggregate statistics about MRD tests. Use this to answer questions like "How many MRD tests are available?" or "Which vendors have the most tests?" Without group_by: returns {"total": N} With group_by: returns {"total": N, "by_{field}": {"value1": count, ...}} Use openonco_list_vendors first to see available vendors for filtering.

Openonco Count Tds

Count TDS (Treatment Decision Support) tests with optional grouping. Get aggregate statistics about TDS tests. Use this to answer questions like "How many CGP panels exist?" or "How many lab services vs IVD kits?" Without group_by: returns {"total": N} With group_by: returns {"total": N, "by_{field}": {"value1": count, ...}} Tip: group_by='productType' shows Central Lab Service vs Laboratory IVD Kit.

Openonco Get Ecd

Get complete details of a single ECD (Early Cancer Detection) test. Retrieves ALL fields for one test, including stage-specific sensitivity, specificity, PPV, NPV, price, and regulatory status. Use this after openonco_search_ecd to get full details of a specific test. Provide either 'id' (e.g., 'ecd-1') or 'name' (e.g., 'Galleri'). Returns JSON object with all fields, or error with NOT_FOUND if test doesn't exist.

Openonco Get Hct

Get complete details of a single HCT (Hereditary Cancer Testing) test. Retrieves ALL fields for one test, including genes analyzed, cancer syndromes covered, sample requirements, and regulatory status. Use this after openonco_search_hct to get full details of a specific test. Provide either 'id' (e.g., 'hct-1') or 'name' (e.g., 'myRisk'). Returns JSON object with all fields, or error with NOT_FOUND if test doesn't exist.

Openonco Get Mrd

Get complete details of a single MRD (Molecular Residual Disease) test. Retrieves ALL fields for one test, including sensitivity, specificity, LOD, turnaround times, clinical settings, and regulatory status. Use this after openonco_search_mrd to get full details of a specific test. Provide either 'id' (e.g., 'mrd-1') or 'name' (e.g., 'Signatera'). Returns JSON object with all fields, or error with NOT_FOUND if test doesn't exist.

Openonco Get Tds

Get complete details of a single TDS (Treatment Decision Support) test. Retrieves ALL fields for one test, including genes analyzed, biomarkers reported, FDA CDx count, turnaround time, price, and NCCN alignment claims. Use this after openonco_search_tds to get full details of a specific test. Provide either 'id' (e.g., 'tds-1') or 'name' (e.g., 'FoundationOne CDx'). Returns JSON object with all fields, or error with NOT_FOUND if test doesn't exist.

Openonco List Cancer Types

List all cancer types covered by oncology diagnostic tests. Use this to discover available cancer types before searching or filtering. Helpful for answering "What cancers are covered?" or building filter options. Returns JSON array of cancer type names sorted alphabetically. Filter by category to see cancer types in specific test types only.

Openonco List Categories

List all test categories with metadata and current test counts. Use this FIRST to understand what data is available. Returns the four oncology diagnostic test categories: MRD, ECD, HCT, TDS. Each category includes: id, name, shortName, description, testCount. The testCount reflects the actual number of tests currently in each category. This is a good starting point for users new to the OpenOnco data.

Openonco List Vendors

List all vendors offering oncology diagnostic tests. Use this to discover available vendors before searching or filtering. Helpful for answering "What companies offer MRD tests?" or building autocomplete suggestions for vendor names. Returns JSON array of vendor names sorted alphabetically. Filter by category to see vendors in specific test types only.

Openonco Search Ecd

Search and filter ECD (Early Cancer Detection) tests. ECD tests screen for cancer in asymptomatic individuals before symptoms appear. Use this when users ask about cancer screening, MCED (multi-cancer early detection), liquid biopsy screening, or comparing screening test costs and accuracy. Tip: Filter by test_scope='Multi-cancer' for MCED tests like Galleri. Use openonco_get_ecd with a test ID for full details including stage sensitivity. Returns JSON array of matching tests. Empty array []

Openonco Search Hct

Search and filter HCT (Hereditary Cancer Testing) tests. HCT tests identify inherited genetic mutations that increase cancer risk, such as BRCA1/BRCA2 for breast/ovarian cancer or Lynch syndrome genes. Use this when users ask about genetic risk assessment, inherited cancer syndromes, or family history-based testing. Tip: Use openonco_get_hct with a test ID for full details including genes covered. Filter by cancer_type to find tests covering specific hereditary cancer syndromes. Returns JSON

Openonco Search Mrd

Search and filter MRD (Molecular Residual Disease) tests. MRD tests detect residual cancer after treatment via ctDNA in blood samples. Use this when users ask about post-treatment monitoring, recurrence detection, or comparing ctDNA-based MRD assays from different vendors. Tip: Use openonco_list_vendors or openonco_list_cancer_types first to discover available filter values. Use openonco_get_mrd with a test ID for full details. Returns JSON array of matching tests. Empty array [] if no matche

Openonco Search Tds

Search and filter TDS (Treatment Decision Support) tests. TDS tests guide treatment via comprehensive genomic profiling (CGP), identifying actionable mutations for targeted therapies and immunotherapy decisions. Use this when users ask about tumor profiling, NGS panels, or companion diagnostics. Tip: Filter by has_fda_cdx=true for tests with FDA companion diagnostic approvals. Use min_genes to find panels with sufficient gene coverage for specific needs. Returns JSON array of matching tests.